Adenosine A2A Receptors in the Rat Prelimbic Medial Prefrontal Cortex Control Delay-Based Cost-Benefit Decision Making

Adenosine A2A Receptors in the Rat Prelimbic Medial Prefrontal Cortex Control Delay-Based Cost-Benefit Decision Making

Adenosine A2A receptors (A2ARs) were recently described to control synaptic plasticity and network activity in the prefrontal cortex (PFC). We now probed the role of these PFC A2AR by evaluating the behavioral performance (locomotor activity, anxiety-related behavior, cost-benefit decision making an...

Full description

Bibliographic Details
Main Authors: Douglas T. Leffa, Pablo Pandolfo, Nélio Gonçalves, Nuno J. Machado, Carolina M. de Souza, Joana I. Real, António C. Silva, Henrique B. Silva, Attila Köfalvi, Rodrigo A. Cunha, Samira G. Ferreira
Format: Article
Language:English
Published: Frontiers Media S.A. 2018-12-01
Series:Frontiers in Molecular Neuroscience
Subjects:
adenosine A2A receptors
impulsive choice
prefrontal cortex (PFC)
anxiety
working memory
cost-benefit decision making
Online Access:https://www.frontiersin.org/article/10.3389/fnmol.2018.00475/full

Internet

https://www.frontiersin.org/article/10.3389/fnmol.2018.00475/full

Similar Items