Selective survival and maturation of adult-born dentate granule cells expressing the immediate early gene Arc/Arg3.1.

Progenitor cells in the adult dentate gyrus provide a constant supply of neuronal precursors, yet only a small fraction of these cells survive and develop into mature dentate granule cells (DGCs). A major challenge of current research is thus to understand the stringent selection process that govern...

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Bibliographic Details
Main Authors: Sjoukje D Kuipers, Adrian Tiron, Jonathan Soule, Elhoucine Messaoudi, Andrea Trentani, Clive R Bramham
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2009-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC2654102?pdf=render