Oral administration of piperine for the control of aflatoxin intoxication in rats

Aflatoxins are mycotoxins that have important toxic effects on human and animal health, even if consumed at low doses. The oral administration of piperine (1.12 mg/kg) during 23 days in rats seemingly interfered with the toxicity of aflatoxins, decreasing hepatic injuries and the leukocyte depletion...

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Main Authors: Thalita B. Gagini, Robson E. Silva, Isabela S. Castro, Breno A. Soares, Marco E.F. Lima, Marilene F. Brito, Carlos Mazur, Glória M. Direito, Maria das Graças M. Danelli
Format: Article
Language:English
Published: Sociedade Brasileira de Microbiologia 2010-06-01
Series:Brazilian Journal of Microbiology
Subjects:
Online Access:http://www.scielo.br/scielo.php?script=sci_arttext&pid=S1517-83822010000200013
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spelling doaj-7f70f55115414fe2a1927abafe8b58652020-11-24T22:43:16ZengSociedade Brasileira de MicrobiologiaBrazilian Journal of Microbiology1517-83821678-44052010-06-0141234534810.1590/S1517-83822010000200013Oral administration of piperine for the control of aflatoxin intoxication in ratsThalita B. GaginiRobson E. SilvaIsabela S. CastroBreno A. SoaresMarco E.F. LimaMarilene F. BritoCarlos MazurGlória M. DireitoMaria das Graças M. DanelliAflatoxins are mycotoxins that have important toxic effects on human and animal health, even if consumed at low doses. The oral administration of piperine (1.12 mg/kg) during 23 days in rats seemingly interfered with the toxicity of aflatoxins, decreasing hepatic injuries and the leukocyte depletion in experimentally intoxicated animals.http://www.scielo.br/scielo.php?script=sci_arttext&pid=S1517-83822010000200013aflatoxinspiperineexperimental intoxicationrats
collection DOAJ
language English
format Article
sources DOAJ
author Thalita B. Gagini
Robson E. Silva
Isabela S. Castro
Breno A. Soares
Marco E.F. Lima
Marilene F. Brito
Carlos Mazur
Glória M. Direito
Maria das Graças M. Danelli
spellingShingle Thalita B. Gagini
Robson E. Silva
Isabela S. Castro
Breno A. Soares
Marco E.F. Lima
Marilene F. Brito
Carlos Mazur
Glória M. Direito
Maria das Graças M. Danelli
Oral administration of piperine for the control of aflatoxin intoxication in rats
Brazilian Journal of Microbiology
aflatoxins
piperine
experimental intoxication
rats
author_facet Thalita B. Gagini
Robson E. Silva
Isabela S. Castro
Breno A. Soares
Marco E.F. Lima
Marilene F. Brito
Carlos Mazur
Glória M. Direito
Maria das Graças M. Danelli
author_sort Thalita B. Gagini
title Oral administration of piperine for the control of aflatoxin intoxication in rats
title_short Oral administration of piperine for the control of aflatoxin intoxication in rats
title_full Oral administration of piperine for the control of aflatoxin intoxication in rats
title_fullStr Oral administration of piperine for the control of aflatoxin intoxication in rats
title_full_unstemmed Oral administration of piperine for the control of aflatoxin intoxication in rats
title_sort oral administration of piperine for the control of aflatoxin intoxication in rats
publisher Sociedade Brasileira de Microbiologia
series Brazilian Journal of Microbiology
issn 1517-8382
1678-4405
publishDate 2010-06-01
description Aflatoxins are mycotoxins that have important toxic effects on human and animal health, even if consumed at low doses. The oral administration of piperine (1.12 mg/kg) during 23 days in rats seemingly interfered with the toxicity of aflatoxins, decreasing hepatic injuries and the leukocyte depletion in experimentally intoxicated animals.
topic aflatoxins
piperine
experimental intoxication
rats
url http://www.scielo.br/scielo.php?script=sci_arttext&pid=S1517-83822010000200013
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