Neurofilament light as a blood biomarker for neurodegeneration in Down syndrome

Neurofilament light as a blood biomarker for neurodegeneration in Down syndrome

Abstract Background Down syndrome (DS) may be considered a genetic form of Alzheimer’s disease (AD) due to universal development of AD neuropathology, but diagnosis and treatment trials are hampered by a lack of reliable blood biomarkers. A potential biomarker is neurofilament light (NF-L), due to i...

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Bibliographic Details
Main Authors: Andre Strydom, Amanda Heslegrave, Carla M. Startin, Kin Y. Mok, John Hardy, Jurgen Groet, Dean Nizetic, Henrik Zetterberg, The LonDownS Consortium
Format: Article
Language:English
Published: BMC 2018-04-01
Series:Alzheimer’s Research & Therapy
Subjects:
Down syndrome
Alzheimer’s disease
Dementia
Neurofilament light
Biomarker
Online Access:http://link.springer.com/article/10.1186/s13195-018-0367-x

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