Mutations in NOTCH3 Gene may Promote the Clinical Presentation of Spinocerebellar Ataxia Type 37 Caused by Mutations in DAB1 Gene

Mutations in NOTCH3 Gene may Promote the Clinical Presentation of Spinocerebellar Ataxia Type 37 Caused by Mutations in DAB1 Gene

Background: Autosomal dominant spinocerebellar ataxia type 37 (SCA37) and Cerebral autosomal dominant arteriopathy with subcortical infarct and leukoencephalopathy (CADASIL) result from DAB1 and NOTCH3 gene mutations, respectively.Methods: In addition to conventional diagnostic methods, next-generat...

Full description

Bibliographic Details
Main Authors: Zhao-Wei Wang, Li-Ping Wang, Ye Du, Qi Liu
Format: Article
Language:English
Published: Frontiers Media S.A. 2021-06-01
Series:Frontiers in Molecular Biosciences
Subjects:
SAC37
CADASIL
Dab1
Notch3
rare diseases
Online Access:https://www.frontiersin.org/articles/10.3389/fmolb.2021.668312/full

Similar Items

Similar Items