Structure-function relationships of lipoprotein lipase: mutation analysis and mutagenesis of the loop region

Structure-function relationships of lipoprotein lipase: mutation analysis and mutagenesis of the loop region

The molecular models of two microbial lipases and human pancreatic lipase (PL) have suggested the existence of common structural motifs including a buried active site shielded by an amphipathic surface loop. In an effort to explore the role of residues comprising the loop of lipoprotein lipase (LPL)...

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Bibliographic Details
Main Authors: HE Henderson, Y Ma, MS Liu, I Clark-Lewis, DL Maeder, JJ Kastelein, JD Brunzell, MR Hayden
Format: Article
Language:English
Published: Elsevier 1993-09-01
Series:Journal of Lipid Research
Online Access:http://www.sciencedirect.com/science/article/pii/S0022227520369522

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