Evaluation of the Prevalence of Chronic Kidney Disease and Rates of Oral Antidiabetic Prescribing in Accordance with Guidelines and Manufacturer Recommendations in Type 2 Diabetic Patients within a Long-Term Care Setting

This retrospective study assessed the prevalence of moderate to severe chronic kidney disease (CKD) among nursing home (NH) residents with type 2 diabetes. The pattern of oral antidiabetic drug (OAD) use and their concordance with the National Kidney Foundation (NKF) guideline and prescribing info...

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Main Authors: Ning Wu, Xia Yu, Mallik Greene, Gary Oderda
Format: Article
Language:English
Published: Hindawi Limited 2014-01-01
Series:International Journal of Nephrology
Online Access:http://dx.doi.org/10.1155/2014/151706
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spelling doaj-7f48e78f881642189bdc8b3155a65e5f2020-11-25T02:40:12ZengHindawi LimitedInternational Journal of Nephrology2090-214X2090-21582014-01-01201410.1155/2014/151706151706Evaluation of the Prevalence of Chronic Kidney Disease and Rates of Oral Antidiabetic Prescribing in Accordance with Guidelines and Manufacturer Recommendations in Type 2 Diabetic Patients within a Long-Term Care SettingNing Wu0Xia Yu1Mallik Greene2Gary Oderda3Health Economics and Epidemiology, Evidera, 430 Bedford Street, Suite 300, Lexington, MA 02420, USAHealth Economics and Epidemiology, Evidera, 430 Bedford Street, Suite 300, Lexington, MA 02420, USABoehringer Ingelheim Pharmaceuticals, Inc., 900 Ridgebury Road, Ridgefield, CT 06877, USAUniversity of Utah School of Pharmacy, 30 South 2000 East, Salt Lake City, UT 84112, USAThis retrospective study assessed the prevalence of moderate to severe chronic kidney disease (CKD) among nursing home (NH) residents with type 2 diabetes. The pattern of oral antidiabetic drug (OAD) use and their concordance with the National Kidney Foundation (NKF) guideline and prescribing information (PI) was also assessed. About half (47%) of diabetic residents had moderate to severe CKD. A little over a quarter of the 186 residents using OADs received at least one NKF-discordant OAD prescription. Metformin was the most commonly misused OAD. PI nonconcordance was observed in 58.6% of residents and was highest in glipizide and metformin users. With the high prevalence of moderate to severe CKD in NH residents with diabetes, physicians should consider residents’ renal function when choosing treatment plans and review treatments regularly to check compliance with the NKF guidelines or PIs.http://dx.doi.org/10.1155/2014/151706
collection DOAJ
language English
format Article
sources DOAJ
author Ning Wu
Xia Yu
Mallik Greene
Gary Oderda
spellingShingle Ning Wu
Xia Yu
Mallik Greene
Gary Oderda
Evaluation of the Prevalence of Chronic Kidney Disease and Rates of Oral Antidiabetic Prescribing in Accordance with Guidelines and Manufacturer Recommendations in Type 2 Diabetic Patients within a Long-Term Care Setting
International Journal of Nephrology
author_facet Ning Wu
Xia Yu
Mallik Greene
Gary Oderda
author_sort Ning Wu
title Evaluation of the Prevalence of Chronic Kidney Disease and Rates of Oral Antidiabetic Prescribing in Accordance with Guidelines and Manufacturer Recommendations in Type 2 Diabetic Patients within a Long-Term Care Setting
title_short Evaluation of the Prevalence of Chronic Kidney Disease and Rates of Oral Antidiabetic Prescribing in Accordance with Guidelines and Manufacturer Recommendations in Type 2 Diabetic Patients within a Long-Term Care Setting
title_full Evaluation of the Prevalence of Chronic Kidney Disease and Rates of Oral Antidiabetic Prescribing in Accordance with Guidelines and Manufacturer Recommendations in Type 2 Diabetic Patients within a Long-Term Care Setting
title_fullStr Evaluation of the Prevalence of Chronic Kidney Disease and Rates of Oral Antidiabetic Prescribing in Accordance with Guidelines and Manufacturer Recommendations in Type 2 Diabetic Patients within a Long-Term Care Setting
title_full_unstemmed Evaluation of the Prevalence of Chronic Kidney Disease and Rates of Oral Antidiabetic Prescribing in Accordance with Guidelines and Manufacturer Recommendations in Type 2 Diabetic Patients within a Long-Term Care Setting
title_sort evaluation of the prevalence of chronic kidney disease and rates of oral antidiabetic prescribing in accordance with guidelines and manufacturer recommendations in type 2 diabetic patients within a long-term care setting
publisher Hindawi Limited
series International Journal of Nephrology
issn 2090-214X
2090-2158
publishDate 2014-01-01
description This retrospective study assessed the prevalence of moderate to severe chronic kidney disease (CKD) among nursing home (NH) residents with type 2 diabetes. The pattern of oral antidiabetic drug (OAD) use and their concordance with the National Kidney Foundation (NKF) guideline and prescribing information (PI) was also assessed. About half (47%) of diabetic residents had moderate to severe CKD. A little over a quarter of the 186 residents using OADs received at least one NKF-discordant OAD prescription. Metformin was the most commonly misused OAD. PI nonconcordance was observed in 58.6% of residents and was highest in glipizide and metformin users. With the high prevalence of moderate to severe CKD in NH residents with diabetes, physicians should consider residents’ renal function when choosing treatment plans and review treatments regularly to check compliance with the NKF guidelines or PIs.
url http://dx.doi.org/10.1155/2014/151706
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