Aging boosts antiviral CD8+T cell memory through improved engagement of diversified recall response determinants.

Aging boosts antiviral CD8+T cell memory through improved engagement of diversified recall response determinants.

The determinants of protective CD8+ memory T cell (CD8+TM) immunity remain incompletely defined and may in fact constitute an evolving agency as aging CD8+TM progressively acquire enhanced rather than impaired recall capacities. Here, we show that old as compared to young antiviral CD8+TM more effec...

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Bibliographic Details
Main Authors: Bennett Davenport, Jens Eberlein, Tom T Nguyen, Francisco Victorino, Kevin Jhun, Haedar Abuirqeba, Verena van der Heide, Peter Heeger, Dirk Homann
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2019-11-01
Series:PLoS Pathogens
Online Access:https://doi.org/10.1371/journal.ppat.1008144

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https://doi.org/10.1371/journal.ppat.1008144

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