Autologous Mesenchymal Stem Cells Prevent Transplant Arteriosclerosis by Enhancing Local Expression of Interleukin-10, Interferon-γ, and Indoleamine 2,3-dioxygenase

Autologous Mesenchymal Stem Cells Prevent Transplant Arteriosclerosis by Enhancing Local Expression of Interleukin-10, Interferon-γ, and Indoleamine 2,3-dioxygenase

Transplant arteriosclerosis (TA) remains the major limitation of long-term graft survival in heart transplantation despite the advances in immunosuppressants. Mesenchymal stem cells (MSCs) have been demonstrated to suppress allogeneic immune responses by numerous in vitro studies. However, the immun...

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Bibliographic Details
Main Authors: Hsiang-Yiang Jui, Cheng-Hsin Lin, Wan-Tseng Hsu, Yi-Ru Liu, Ron-Bin Hsu, Bor-Luen Chiang, Wen-Yih I. Tseng, Ming-Fong Chen, Kenneth K. Wu, Chii-Ming Lee M.D., Ph.D.
Format: Article
Language:English
Published: SAGE Publishing 2012-05-01
Series:Cell Transplantation
Online Access:https://doi.org/10.3727/096368911X627525

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