Autologous Mesenchymal Stem Cells Prevent Transplant Arteriosclerosis by Enhancing Local Expression of Interleukin-10, Interferon-γ, and Indoleamine 2,3-dioxygenase
Transplant arteriosclerosis (TA) remains the major limitation of long-term graft survival in heart transplantation despite the advances in immunosuppressants. Mesenchymal stem cells (MSCs) have been demonstrated to suppress allogeneic immune responses by numerous in vitro studies. However, the immun...
Main Authors: | , , , , , , , , , |
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Format: | Article |
Language: | English |
Published: |
SAGE Publishing
2012-05-01
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Series: | Cell Transplantation |
Online Access: | https://doi.org/10.3727/096368911X627525 |