Exophthalmos: A Forgotten Clinical Sign of Cushing's Syndrome

Exophthalmos: A Forgotten Clinical Sign of Cushing's Syndrome

Exophthalmos is typically associated with Graves' ophthalmopathy. Although originally described by Harvey Cushing, exophthalmos is an underappreciated sign of Cushing's syndrome. We present a case of a 38-year-old female who presented with severe bilateral proptosis and was subsequently di...

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Main Authors: Aldo Schenone Giugni, Shylaja Mani, Subramanian Kannan, Betul Hatipoglu
Format: Article
Language:English
Published: Hindawi Limited 2013-01-01
Series:Case Reports in Endocrinology
Online Access:http://dx.doi.org/10.1155/2013/205208
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spelling doaj-7f3860ad5de147f2961988eb8451ec532020-11-24T21:04:10ZengHindawi LimitedCase Reports in Endocrinology2090-65012090-651X2013-01-01201310.1155/2013/205208205208Exophthalmos: A Forgotten Clinical Sign of Cushing's SyndromeAldo Schenone Giugni0Shylaja Mani1Subramanian Kannan2Betul Hatipoglu3Department of Internal Medicine, Cleveland Clinic Foundation, 9500 Euclid Avenue Desk NA10, Cleveland, OH 44195, USADepartment of Internal Medicine, Cleveland Clinic Foundation, 9500 Euclid Avenue Desk NA10, Cleveland, OH 44195, USADepartment of Endocrinology, Diabetes and Metabolism, Cleveland Clinic Foundation, 9500 Euclid Avenue Desk F20, Cleveland, OH 44195, USADepartment of Endocrinology, Diabetes and Metabolism, Cleveland Clinic Foundation, 9500 Euclid Avenue Desk F20, Cleveland, OH 44195, USAExophthalmos is typically associated with Graves' ophthalmopathy. Although originally described by Harvey Cushing, exophthalmos is an underappreciated sign of Cushing's syndrome. We present a case of a 38-year-old female who presented with severe bilateral proptosis and was subsequently diagnosed with Cushings disease. We discuss the possible mechanisms causing exophthalmos in patients with either endogenous or exogenous hypercortisolemia.http://dx.doi.org/10.1155/2013/205208
collection DOAJ
language English
format Article
sources DOAJ
author Aldo Schenone Giugni
Shylaja Mani
Subramanian Kannan
Betul Hatipoglu
spellingShingle Aldo Schenone Giugni
Shylaja Mani
Subramanian Kannan
Betul Hatipoglu
Exophthalmos: A Forgotten Clinical Sign of Cushing's Syndrome
Case Reports in Endocrinology
author_facet Aldo Schenone Giugni
Shylaja Mani
Subramanian Kannan
Betul Hatipoglu
author_sort Aldo Schenone Giugni
title Exophthalmos: A Forgotten Clinical Sign of Cushing's Syndrome
title_short Exophthalmos: A Forgotten Clinical Sign of Cushing's Syndrome
title_full Exophthalmos: A Forgotten Clinical Sign of Cushing's Syndrome
title_fullStr Exophthalmos: A Forgotten Clinical Sign of Cushing's Syndrome
title_full_unstemmed Exophthalmos: A Forgotten Clinical Sign of Cushing's Syndrome
title_sort exophthalmos: a forgotten clinical sign of cushing's syndrome
publisher Hindawi Limited
series Case Reports in Endocrinology
issn 2090-6501
2090-651X
publishDate 2013-01-01
description Exophthalmos is typically associated with Graves' ophthalmopathy. Although originally described by Harvey Cushing, exophthalmos is an underappreciated sign of Cushing's syndrome. We present a case of a 38-year-old female who presented with severe bilateral proptosis and was subsequently diagnosed with Cushings disease. We discuss the possible mechanisms causing exophthalmos in patients with either endogenous or exogenous hypercortisolemia.
url http://dx.doi.org/10.1155/2013/205208
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AT shylajamani exophthalmosaforgottenclinicalsignofcushingssyndrome
AT subramaniankannan exophthalmosaforgottenclinicalsignofcushingssyndrome
AT betulhatipoglu exophthalmosaforgottenclinicalsignofcushingssyndrome
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