Identification of the Anti-Infective Aborycin Biosynthetic Gene Cluster from Deep-Sea-Derived <i>Streptomyces</i> sp. SCSIO ZS0098 Enables Production in a Heterologous Host

Identification of the Anti-Infective Aborycin Biosynthetic Gene Cluster from Deep-Sea-Derived <i>Streptomyces</i> sp. SCSIO ZS0098 Enables Production in a Heterologous Host

Aborycin is a ribosomally synthesized member of the type I lasso peptide natural products. In the present study, aborycin was isolated and identified from the deep-sea-derived microbe <i>Streptomyces</i> sp. SCSIO ZS0098. The aborycin biosynthetic gene cluster (<i>abo</i>) wa...

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Bibliographic Details
Main Authors: Mingwei Shao, Juying Ma, Qinglian Li, Jianhua Ju
Format: Article
Language:English
Published: MDPI AG 2019-02-01
Series:Marine Drugs
Subjects:
<i>Streptomyces</i> sp. SCSIO ZS0098
aborycin
heterogenous expression
antibacterial activity
Online Access:https://www.mdpi.com/1660-3397/17/2/127

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