Mathematical Modelling of Molecular Pathways Enabling Tumour Cell Invasion and Migration.

Understanding the etiology of metastasis is very important in clinical perspective, since it is estimated that metastasis accounts for 90% of cancer patient mortality. Metastasis results from a sequence of multiple steps including invasion and migration. The early stages of metastasis are tightly co...

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Bibliographic Details
Main Authors: David P A Cohen, Loredana Martignetti, Sylvie Robine, Emmanuel Barillot, Andrei Zinovyev, Laurence Calzone
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2015-11-01
Series:PLoS Computational Biology
Online Access:https://doi.org/10.1371/journal.pcbi.1004571