Recent Advances of Stem Cell Therapy for Retinitis Pigmentosa

Retinitis pigmentosa (RP) is a group of inherited retinal disorders characterized by progressive loss of photoreceptors and eventually leads to retina degeneration and atrophy. Until now, the exact pathogenesis and etiology of this disease has not been clear, and many approaches for RP therapies hav...

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Main Authors:	Yuxi He, Yan Zhang, Xin Liu, Emma Ghazaryan, Ying Li, Jianan Xie, Guanfang Su
Format:	Article
Language:	English
Published:	MDPI AG 2014-08-01
Series:	International Journal of Molecular Sciences
Subjects:	retinitis pigmentosa bone marrow-derived mesenchymal stem cells stem cell transplantation
Online Access:	http://www.mdpi.com/1422-0067/15/8/14456

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spelling	doaj-7f285dde31404d2fb837be0ee6e575952020-11-24T21:45:47ZengMDPI AGInternational Journal of Molecular Sciences1422-00672014-08-01158144561447410.3390/ijms150814456ijms150814456Recent Advances of Stem Cell Therapy for Retinitis PigmentosaYuxi He0Yan Zhang1Xin Liu2Emma Ghazaryan3Ying Li4Jianan Xie5Guanfang Su6Department of Ophthalmology, Second Hospital, Jilin University, Ziqiang Street No. 218, Changchun 130041, Jilin, ChinaDepartment of Ophthalmology, Second Hospital, Jilin University, Ziqiang Street No. 218, Changchun 130041, Jilin, ChinaDepartment of Ophthalmology, Second Hospital, Jilin University, Ziqiang Street No. 218, Changchun 130041, Jilin, ChinaDepartment of Ophthalmology, Second Hospital, Jilin University, Ziqiang Street No. 218, Changchun 130041, Jilin, ChinaDepartment of Ophthalmology, Second Hospital, Jilin University, Ziqiang Street No. 218, Changchun 130041, Jilin, ChinaDepartment of Ophthalmology, Second Hospital, Jilin University, Ziqiang Street No. 218, Changchun 130041, Jilin, ChinaDepartment of Ophthalmology, Second Hospital, Jilin University, Ziqiang Street No. 218, Changchun 130041, Jilin, ChinaRetinitis pigmentosa (RP) is a group of inherited retinal disorders characterized by progressive loss of photoreceptors and eventually leads to retina degeneration and atrophy. Until now, the exact pathogenesis and etiology of this disease has not been clear, and many approaches for RP therapies have been carried out in animals and in clinical trials. In recent years, stem cell transplantation-based attempts made some progress, especially the transplantation of bone marrow-derived mesenchymal stem cells (BMSCs). This review will provide an overview of stem cell-based treatment of RP and its main problems, to provide evidence for the safety and feasibility for further clinical treatment.http://www.mdpi.com/1422-0067/15/8/14456retinitis pigmentosabone marrow-derived mesenchymal stem cellsstem cell transplantation
collection	DOAJ
language	English
format	Article
sources	DOAJ
author	Yuxi He Yan Zhang Xin Liu Emma Ghazaryan Ying Li Jianan Xie Guanfang Su
spellingShingle	Yuxi He Yan Zhang Xin Liu Emma Ghazaryan Ying Li Jianan Xie Guanfang Su Recent Advances of Stem Cell Therapy for Retinitis Pigmentosa International Journal of Molecular Sciences retinitis pigmentosa bone marrow-derived mesenchymal stem cells stem cell transplantation
author_facet	Yuxi He Yan Zhang Xin Liu Emma Ghazaryan Ying Li Jianan Xie Guanfang Su
author_sort	Yuxi He
title	Recent Advances of Stem Cell Therapy for Retinitis Pigmentosa
title_short	Recent Advances of Stem Cell Therapy for Retinitis Pigmentosa
title_full	Recent Advances of Stem Cell Therapy for Retinitis Pigmentosa
title_fullStr	Recent Advances of Stem Cell Therapy for Retinitis Pigmentosa
title_full_unstemmed	Recent Advances of Stem Cell Therapy for Retinitis Pigmentosa
title_sort	recent advances of stem cell therapy for retinitis pigmentosa
publisher	MDPI AG
series	International Journal of Molecular Sciences
issn	1422-0067
publishDate	2014-08-01
description	Retinitis pigmentosa (RP) is a group of inherited retinal disorders characterized by progressive loss of photoreceptors and eventually leads to retina degeneration and atrophy. Until now, the exact pathogenesis and etiology of this disease has not been clear, and many approaches for RP therapies have been carried out in animals and in clinical trials. In recent years, stem cell transplantation-based attempts made some progress, especially the transplantation of bone marrow-derived mesenchymal stem cells (BMSCs). This review will provide an overview of stem cell-based treatment of RP and its main problems, to provide evidence for the safety and feasibility for further clinical treatment.
topic	retinitis pigmentosa bone marrow-derived mesenchymal stem cells stem cell transplantation
url	http://www.mdpi.com/1422-0067/15/8/14456
work_keys_str_mv	AT yuxihe recentadvancesofstemcelltherapyforretinitispigmentosa AT yanzhang recentadvancesofstemcelltherapyforretinitispigmentosa AT xinliu recentadvancesofstemcelltherapyforretinitispigmentosa AT emmaghazaryan recentadvancesofstemcelltherapyforretinitispigmentosa AT yingli recentadvancesofstemcelltherapyforretinitispigmentosa AT jiananxie recentadvancesofstemcelltherapyforretinitispigmentosa AT guanfangsu recentadvancesofstemcelltherapyforretinitispigmentosa
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Recent Advances of Stem Cell Therapy for Retinitis Pigmentosa

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