FGFR1 Expression and Role in Migration in Low and High Grade Pediatric Gliomas

FGFR1 Expression and Role in Migration in Low and High Grade Pediatric Gliomas

The heterogeneous and invasive nature of pediatric gliomas poses significant treatment challenges, highlighting the importance of identifying novel chemotherapeutic targets. Recently, recurrent Fibroblast growth factor receptor 1 (FGFR1) mutations in pediatric gliomas have been reported. Here, we ex...

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Bibliographic Details
Main Authors: Naomi Egbivwie, Julia V. Cockle, Matthew Humphries, Azzam Ismail, Filomena Esteves, Claire Taylor, Katherine Karakoula, Ruth Morton, Tracy Warr, Susan C. Short, Anke Brüning-Richardson
Format: Article
Language:English
Published: Frontiers Media S.A. 2019-03-01
Series:Frontiers in Oncology
Subjects:
pediatric gliomas
FGFR1
migration
immunohistochemistry
inhibitors
Online Access:https://www.frontiersin.org/article/10.3389/fonc.2019.00103/full

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