Effects of Comorbidities on Asthma Hospitalization and Mortality Rates: A Systematic Review

Background. Recent studies have shown that patients diagnosed with asthma who have other chronic comorbidities have severely worse medical outcomes. However, the number of available published studies in this field is lacking. The aim of this study was to determine the effects of comorbidities in ast...

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Main Authors: Masoud Mahdavian, Blake H. Power, Shabnam Asghari, Jordan C. Pike
Format: Article
Language:English
Published: Hindawi Limited 2018-01-01
Series:Canadian Respiratory Journal
Online Access:http://dx.doi.org/10.1155/2018/6460379
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spelling doaj-7f15f242c0ef41b5ba03d9062e789d902021-07-02T10:35:41ZengHindawi LimitedCanadian Respiratory Journal1198-22411916-72452018-01-01201810.1155/2018/64603796460379Effects of Comorbidities on Asthma Hospitalization and Mortality Rates: A Systematic ReviewMasoud Mahdavian0Blake H. Power1Shabnam Asghari2Jordan C. Pike3Division of Respirology, Department of Medicine, Faculty of Medicine, Memorial University of Newfoundland, St. John’s, NL, A1C 5B8, CanadaFaculty of Medicine, Memorial University of Newfoundland, St. John’s, NL, A1B 3V6, CanadaFaculty of Medicine, Memorial University of Newfoundland, St. John’s, NL, A1B 3V6, CanadaLibrarian II, Eastern Health, Department of Research, St. John’s, CanadaBackground. Recent studies have shown that patients diagnosed with asthma who have other chronic comorbidities have severely worse medical outcomes. However, the number of available published studies in this field is lacking. The aim of this study was to determine the effects of comorbidities in asthmatic patients based on hospitalization and mortality rates. Methods. A systematic review was conducted. Data were obtained from the electronic databases PubMed, CINAHL, and Cochrane until June 15, 2018. The primary objective of this study was to determine the effects of comorbidities on asthma hospitalization and mortality. The secondary objective was to analyze the effects of asthma comorbidity with certain chronic diseases, including COPD, obesity, obstructive sleep apnea, mental illness (anxiety and depression), diabetes mellitus, hypertension, myocardial ischemia, rhinitis, and sinusitis on asthma hospitalization and mortality. Results. From potential 687 articles, only 9 were chosen based on our study inclusion criteria. Almost half of these articles were related to asthma/COPD comorbidity. There were no articles found for hypertension, myocardial ischemia, rhinitis, or sinusitis based on our inclusion/exclusion factors. Each of these 9 published articles had shown an increase in rates of hospitalization, length of stay, and/or mortality, due to asthma-related symptoms, compared to asthma-only patients. Conclusion. There was determined to be a large discrepancy between the available research for various types of comorbid conditions presenting with asthma that focus on hospitalization and mortality rates. The current available literature suggests a large impact that these comorbid diseases can have on asthma-related symptoms when present together, severely affecting a patient’s quality of life. We propose that further research on the effects of these comorbidities on asthma mortality and hospitalization can yield beneficial results to improve the management of asthmatic patients.http://dx.doi.org/10.1155/2018/6460379
collection DOAJ
language English
format Article
sources DOAJ
author Masoud Mahdavian
Blake H. Power
Shabnam Asghari
Jordan C. Pike
spellingShingle Masoud Mahdavian
Blake H. Power
Shabnam Asghari
Jordan C. Pike
Effects of Comorbidities on Asthma Hospitalization and Mortality Rates: A Systematic Review
Canadian Respiratory Journal
author_facet Masoud Mahdavian
Blake H. Power
Shabnam Asghari
Jordan C. Pike
author_sort Masoud Mahdavian
title Effects of Comorbidities on Asthma Hospitalization and Mortality Rates: A Systematic Review
title_short Effects of Comorbidities on Asthma Hospitalization and Mortality Rates: A Systematic Review
title_full Effects of Comorbidities on Asthma Hospitalization and Mortality Rates: A Systematic Review
title_fullStr Effects of Comorbidities on Asthma Hospitalization and Mortality Rates: A Systematic Review
title_full_unstemmed Effects of Comorbidities on Asthma Hospitalization and Mortality Rates: A Systematic Review
title_sort effects of comorbidities on asthma hospitalization and mortality rates: a systematic review
publisher Hindawi Limited
series Canadian Respiratory Journal
issn 1198-2241
1916-7245
publishDate 2018-01-01
description Background. Recent studies have shown that patients diagnosed with asthma who have other chronic comorbidities have severely worse medical outcomes. However, the number of available published studies in this field is lacking. The aim of this study was to determine the effects of comorbidities in asthmatic patients based on hospitalization and mortality rates. Methods. A systematic review was conducted. Data were obtained from the electronic databases PubMed, CINAHL, and Cochrane until June 15, 2018. The primary objective of this study was to determine the effects of comorbidities on asthma hospitalization and mortality. The secondary objective was to analyze the effects of asthma comorbidity with certain chronic diseases, including COPD, obesity, obstructive sleep apnea, mental illness (anxiety and depression), diabetes mellitus, hypertension, myocardial ischemia, rhinitis, and sinusitis on asthma hospitalization and mortality. Results. From potential 687 articles, only 9 were chosen based on our study inclusion criteria. Almost half of these articles were related to asthma/COPD comorbidity. There were no articles found for hypertension, myocardial ischemia, rhinitis, or sinusitis based on our inclusion/exclusion factors. Each of these 9 published articles had shown an increase in rates of hospitalization, length of stay, and/or mortality, due to asthma-related symptoms, compared to asthma-only patients. Conclusion. There was determined to be a large discrepancy between the available research for various types of comorbid conditions presenting with asthma that focus on hospitalization and mortality rates. The current available literature suggests a large impact that these comorbid diseases can have on asthma-related symptoms when present together, severely affecting a patient’s quality of life. We propose that further research on the effects of these comorbidities on asthma mortality and hospitalization can yield beneficial results to improve the management of asthmatic patients.
url http://dx.doi.org/10.1155/2018/6460379
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