Overexpression of an endogenous type 2 diacylglycerol acyltransferase in the marine diatom Phaeodactylum tricornutum enhances lipid production and omega-3 long-chain polyunsaturated fatty acid content

Overexpression of an endogenous type 2 diacylglycerol acyltransferase in the marine diatom Phaeodactylum tricornutum enhances lipid production and omega-3 long-chain polyunsaturated fatty acid content

Abstract Background Oleaginous microalgae represent a valuable resource for the production of high-value molecules. Considering the importance of omega-3 long-chain polyunsaturated fatty acids (LC-PUFAs) for human health and nutrition the yields of high-value eicosapentaenoic acid (EPA) and docosahe...

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Bibliographic Details
Main Authors: Richard P. Haslam, Mary L. Hamilton, Chloe K. Economou, Richard Smith, Kirsty L. Hassall, Johnathan A. Napier, Olga Sayanova
Format: Article
Language:English
Published: BMC 2020-05-01
Series:Biotechnology for Biofuels
Subjects:
Acyl-CoA:diacylglycerol acyltransferase (DGAT)
Eicosapentaenoic acid
Docosahexaenoic acid
Triacylgycerol
Omega-3 fatty acids
Phaeodactylum tricornutum
Online Access:http://link.springer.com/article/10.1186/s13068-020-01726-8

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