The ZIP5 ectodomain co-localizes with PrP and may acquire a PrP-like fold that assembles into a dimer.

The ZIP5 ectodomain co-localizes with PrP and may acquire a PrP-like fold that assembles into a dimer.

The cellular prion protein (PrP(C)) was recently observed to co-purify with members of the LIV-1 subfamily of ZIP zinc transporters (LZTs), precipitating the surprising discovery that the prion gene family descended from an ancestral LZT gene. Here, we compared the subcellular distribution and bioph...

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Bibliographic Details
Main Authors: Cosmin L Pocanschi, Sepehr Ehsani, Mohadeseh Mehrabian, Holger Wille, William Reginold, William S Trimble, Hansen Wang, Adelinda Yee, Cheryl H Arrowsmith, Zoltán Bozóky, Lewis E Kay, Julie D Forman-Kay, James M Rini, Gerold Schmitt-Ulms
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2013-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3765157?pdf=render

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