REV3L, a promising target in regulating the chemosensitivity of cervical cancer cells.

REV3L, a promising target in regulating the chemosensitivity of cervical cancer cells.

REV3L, the catalytic subunit of DNA Polymerase ζ (Polζ), plays a significant role in the DNA damage tolerance mechanism of translesion synthesis (TLS). The role of REV3L in chemosensitivity of cervical cancer needs exploration. In the present study, we evaluated the expression of the Polζ protein in...

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Bibliographic Details
Main Authors: Li Yang, Tingyan Shi, Fei Liu, Chunxia Ren, Ziliang Wang, Yingyi Li, Xiaoyu Tu, Gong Yang, Xi Cheng
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2015-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC4364373?pdf=render

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