Novel Resistance Mechanisms to Osimertinib Analysed by Whole-Exome Sequencing in Non-Small Cell Lung Cancer

Novel Resistance Mechanisms to Osimertinib Analysed by Whole-Exome Sequencing in Non-Small Cell Lung Cancer

Zhen Wu,1 Wei Zhao,1 Zhen Yang,1 Yue Ming Wang,2 Yu Dai,1 Liang-An Chen1,2 1Respiratory Department of Chinese PLA General Hospital, Beijing, People’s Republic of China; 2School of Medicine, Nankai University, Tianjin, People’s Republic of ChinaCorrespondence: Liang-An Chen IMB 16...

Full description

Bibliographic Details
Main Authors:	Wu Z, Zhao W, Yang Z, Wang YM, Dai Y, Chen LA
Format:	Article
Language:	English
Published:	Dove Medical Press 2021-02-01
Series:	Cancer Management and Research
Subjects:	osimertinib drug resistance whole exome sequencing lung cancer targeted therapy.
Online Access:	https://www.dovepress.com/novel-resistance-mechanisms-to-osimertinib-analysed-by-whole-exome-seq-peer-reviewed-article-CMAR

Similar Items

Whole Exome Sequencing of Chronic Myeloid Leukemia Patients
by: Shaghayegh SABRI, et al.
Published: (2016-03-01)

Patterns of Whole Exome Sequencing in Resected Cholangiocarcinoma
by: Lucas W. Thornblade, et al.
Published: (2021-08-01)

Influence of low tumor content on tumor mutational burden estimation by whole‐exome sequencing and targeted panel sequencing
by: Wenxin Zhang, et al.
Published: (2021-05-01)

Application of targeted panel sequencing and whole exome sequencing for 76 Chinese families with retinitis pigmentosa
by: Handong Dan, et al.
Published: (2020-03-01)

Whole exome sequencing of a patient with metastatic hidradenocarcinoma and review of the literature
by: Eva Gupta, et al.
Published: (2015-02-01)

Lung Adenocarcinoma Harboring EGFR Kinase Domain Duplication (EGFR-KDD) Confers Sensitivity to Osimertinib and Nivolumab: A Case Report
by: Jie Li, et al.
Published: (2020-12-01)

Comprehensive Outline of Whole Exome Sequencing Data Analysis Tools Available in Clinical Oncology
by: Áron Bartha, et al.
Published: (2019-11-01)

Identification of rare paired box 3 variant in strabismus by whole exome sequencing
by: Hui-Min Gong, et al.
Published: (2017-08-01)

Whole exome sequencing of lung adenocarcinoma and lung squamous cell carcinoma in one individual: A case report
by: Yuxi Bai, et al.
Published: (2020-08-01)

From Genomes to GENE-omes: Exome Sequencing Concept and Applications in Crop Improvement
by: Parampreet Kaur, et al.
Published: (2017-12-01)

Evaluation of Whole-Exome Enrichment Solutions: Lessons from the High-End of the Short-Read Sequencing Scale
by: Ana Díaz-de Usera, et al.
Published: (2020-11-01)

Applicability of next generation genetic testing in epilepsy through whole exome sequencing
by: Daniela Catereniuc, et al.
Published: (2020-10-01)

Whole-exome sequencing in familial keratoconus: the challenges of a genetically complex disorder
by: Otávio de Azevedo Magalhães, et al.

Intracranial Activity of Osimertinib Plus Capmatinib in a Patient With EGFR and MET-Driven Lung Cancer: Case Report
by: Oliver Gautschi, MD, et al.
Published: (2021-04-01)

Experiences with Whole Exome Sequencing: A Collective Case Study
by: Mouhlas, Danielle
Published: (2015)

Application of Whole Exome and Targeted Panel Sequencing in the Clinical Molecular Diagnosis of 319 Chinese Families with Inherited Retinal Dystrophy and Comparison Study
by: Likun Wang, et al.
Published: (2018-07-01)

The Personalisation of Glioblastoma Treatment Using Whole Exome Sequencing: A Pilot Study
by: Anne-Marie Garrett, et al.
Published: (2020-02-01)

Platform comparison of detecting copy number variants with microarrays and whole-exome sequencing
by: Joep de Ligt, et al.
Published: (2014-12-01)

A new massively parallel nanoball sequencing platform for whole exome research
by: Yu Xu, et al.
Published: (2019-03-01)

Whole Exome Sequencing in Psoriasis Patients Contributes to Studies of Acitretin Treatment Difference
by: Xingchen Zhou, et al.
Published: (2017-01-01)

Parental understanding of whole exome sequencing: A comparison of perceived and actual understanding.
by: Tolusso, Leandra K.
Published: (2016)

Clinical Utility of Whole Exome Sequencing and Targeted Panels for the Identification of Inborn Errors of Immunity in a Resource-Constrained Setting
by: Clair Engelbrecht, et al.
Published: (2021-05-01)

Genomic characterization of Chinese ovarian clear cell carcinoma identifies driver genes by whole exome sequencing
by: Qin Yang, et al.
Published: (2020-09-01)

Whole-exome sequencing of a pedigree segregating asthma
by: DeWan Andrew T, et al.
Published: (2012-10-01)

Two novel mutations in DNAJC12 identified by whole‐exome sequencing in a patient with mild hyperphenylalaninemia
by: Mengting Li, et al.
Published: (2020-08-01)

Mutation profile of non-small cell lung cancer revealed by next generation sequencing
by: Ya-Sian Chang, et al.
Published: (2021-01-01)

Whole-Exome Sequencing for Identifying Genetic Causes of Intellectual Developmental Disorders
by: Guo YX, et al.
Published: (2021-04-01)

Whole-exome sequencing in 168 Korean patients with inherited retinal degeneration
by: Dae Joong Ma, et al.
Published: (2021-03-01)

Highly Efficient and Comprehensive Identification of Ethyl Methanesulfonate-Induced Mutations in Nicotiana tabacum L. by Whole-Genome and Whole-Exome Sequencing
by: Hisashi Udagawa, et al.
Published: (2021-06-01)

Osimertinib‐induced severe interstitial lung disease: A case report
by: Mengdi Fan, et al.
Published: (2019-07-01)

Fundoscopy-directed genetic testing to re-evaluate negative whole exome sequencing results
by: Ahra Cho, et al.
Published: (2020-01-01)

BALSA: integrated secondary analysis for whole-genome and whole-exome sequencing, accelerated by GPU
by: Ruibang Luo, et al.
Published: (2014-06-01)

Whole Genome Sequencing in the Evaluation of Fetal Structural Anomalies: A Parallel Test with Chromosomal Microarray Plus Whole Exome Sequencing
by: Jia Zhou, et al.
Published: (2021-03-01)

Strategies for whole-exome sequencing analysis in a case series study of familial male infertility
by: Masomeh Askari, et al.
Published: (2020-05-01)

Whole‐exome sequencing provides insights into monogenic disease prevalence in Northwest Russia
by: Yury A. Barbitoff, et al.
Published: (2019-11-01)

Whole-Exome Sequencing in Searching for New Variants Associated With the Development of Parkinson’s Disease
by: Marina V. Shulskaya, et al.
Published: (2018-05-01)

Whole exome sequencing in three families segregating a pediatric case of sarcoidosis
by: Alain Calender, et al.
Published: (2018-03-01)

Delineation of molecular findings by whole-exome sequencing for suspected cases of paediatric-onset mitochondrial diseases in the Southern Chinese population
by: Mandy H.Y. Tsang, et al.
Published: (2020-09-01)

The Role and Challenges of Exome Sequencing in Studies of Human Diseases
by: Zuoheng eWang, et al.
Published: (2013-08-01)

Identification of Novel Candidate Genes for Familial Thyroid Cancer by Whole Exome Sequencing
by: Antiñolo, G., et al.
Published: (2023)

Cannot write session to /tmp/vufind_sessions/sess_3p7eu6hleg1jk7p6b6112msdd4