An Ingestible Electronics for Continuous and Real-Time Intraabdominal Pressure Monitoring

• Main Authors: Chien-Hung Liao, Chi-Tung Cheng, Chih-Chi Chen, Uei-Ming Jow, Chun-Hung Chen, Yen-Liang Lai, Ya-Chuan Chen, Dong-Ru Ho
• Format: Article
• Language: English
• Published: MDPI AG 2021-12-01
• Series: Journal of Personalized Medicine
• Subjects: intraabdominal hypertension; abdominal compartment syndrome; smart capsule; wearable device
• Online Access: https://www.mdpi.com/2075-4426/11/1/12

Abdominal compartment syndrome can be treated through decompressive surgery if intraabdominal hypertension (IAH) can be detected in time. Treatment delays due to manual, conventional intravesical pressure (IVP) monitoring using a Foley catheter have been reported. In this work, we present an innovative gastrointestinal intraluminal pressure (GIP) measurement-based method to monitor and improve pressure-guided relief of intraabdominal pressure (IAP). A novel algorithm for detecting IAH in the gastrointestinal tract of a live porcine model is reported. A wireless pressure-sensing capsule (10 × 13 mm) was developed for absolute measurement. The IAP was estimated during artificial pneumoperitoneum. The pressure waveform-based measurements indicated that the wireless pressure sensor could be used to predict IAP. To enhance GIP monitoring for predicting IAH, the proposed continuous ingestible wireless electronics-based pressure waveform measurement device can be used as a complement to existing modalities. The use of the proposed pressure measurement and communication technology can help provide valuable data for digital health platforms.