Identification, characterization and application of a G-quadruplex structured DNA aptamer against cancer biomarker protein anterior gradient homolog 2.

Identification, characterization and application of a G-quadruplex structured DNA aptamer against cancer biomarker protein anterior gradient homolog 2.

<h4>Background</h4>Anterior gradient homolog 2 (AGR2) is a functional protein with critical roles in a diverse range of biological systems, including vertebrate tissue development, inflammatory tissue injury responses, and cancer progression. Clinical studies have shown that the AGR2 pro...

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Bibliographic Details
Main Authors: Jie Wu, Chi Wang, Xilan Li, Yanling Song, Wei Wang, Cong Li, Jia Hu, Zhi Zhu, Jiuxing Li, Weiyun Zhang, Zhongxian Lu, Chaoyong James Yang
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2012-01-01
Series:PLoS ONE
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/pmid/23029506/pdf/?tool=EBI

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