Hippocampal and prefrontal processing of network topology to simulate the future

The hippocampus is known to support navigation, but how it processes possible paths to aid navigation is unknown. Here Javadiet al. show that entering streets drives hippocampal activity corresponding to the number of future paths, and that prefrontal activity corresponds to path-planning demands.

Bibliographic Details
Main Authors: Amir-Homayoun Javadi, Beatrix Emo, Lorelei R. Howard, Fiona E. Zisch, Yichao Yu, Rebecca Knight, Joao Pinelo Silva, Hugo J. Spiers
Format: Article
Language:English
Published: Nature Publishing Group 2017-03-01
Series:Nature Communications
Online Access:https://doi.org/10.1038/ncomms14652

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