Clinical value of anti-HBc quantification for chronic HBV infection
As the achivement of a major project during the 12th Five-year Plan Period in China, the technique of anti-HBc quantification has been approved for commercial use and holds promise for wide application in clinical practice. Chinese scholars have explored the clinical significance of anti-HBc in vari...
| Main Authors: | , |
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| Format: | Article |
| Language: | zho |
| Published: |
Editorial Department of Journal of Clinical Hepatology
2018-05-01
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| Series: | Linchuang Gandanbing Zazhi |
| Subjects: | |
| Online Access: | http://www.lcgdbzz.org/qk_content.asp?id=9066 |
| Summary: | As the achivement of a major project during the 12th Five-year Plan Period in China, the technique of anti-HBc quantification has been approved for commercial use and holds promise for wide application in clinical practice. Chinese scholars have explored the clinical significance of anti-HBc in various aspects and found that it has great values in the assessment of natural course of chronic hepatitis B virus (HBV) infection and the baseline prediction of antiviral therapy. Studies have shown that anti-HBc is significantly positively correlated with alanine aminotransferase (ALT) and significantly associated with liver inflammation. In chronic HBV infection patients with a normal ALT level, anti-HBc can be used instead as an indicator, with great significance for the development of therapeutic strategy in such patients. |
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| ISSN: | 1001-5256 1001-5256 |