ImmGen report: sexual dimorphism in the immune system transcriptome

Sexual dimorphism is observed frequently in immune disorders, but the underlying insights are still unclear. Here the authors analyze transcriptome and epigenome changes induced by interferon in various mouse immune cell types, and find only a restricted set of sexual dimorphism genes in innate immu...

Full description

Bibliographic Details
Main Authors: Shani Talia Gal-Oz, Barbara Maier, Hideyuki Yoshida, Kumba Seddu, Nitzan Elbaz, Charles Czysz, Or Zuk, Barbara E. Stranger, Hadas Ner-Gaon, Tal Shay
Format: Article
Language:English
Published: Nature Publishing Group 2019-09-01
Series:Nature Communications
Online Access:https://doi.org/10.1038/s41467-019-12348-6