Unusual Chair-Like G-Quadruplex Structures: Heterochiral TBA Analogues Containing Inversion of Polarity Sites

Heterochiral oligodeoxynucleotides based on the thrombin binding aptamer sequence, namely, 5′gg3′-3′TT5′-5′ggtgtgg3′-3′TT5′-5′gg3′ (H1), 5′gg3′-3′TT5′-5′gg3′-3′TGT5′-5′gg3′-3′TT5′-5′gg3′ (H2), and 5′gGTTGgtgtgGTTGg3′ (H3), where lower case letters indicate L-residues, have been investigated in their...

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Bibliographic Details
Main Authors: Antonella Virgilio, Luciano Mayol, Michela Varra, Aldo Galeone, Veronica Esposito
Format: Article
Language:English
Published: Hindawi Limited 2015-01-01
Series:Journal of Chemistry
Online Access:http://dx.doi.org/10.1155/2015/473051