Remarkable functions of sn-3 hydroxy and phosphocholine groups in 1,2-diacyl-sn-glycerolipids to induce clockwise (+)-helicity around the 1,2-diacyl moiety: Evidence from conformation analysis by 1H NMR spectroscopy

Remarkable functions of sn-3 hydroxy and phosphocholine groups in 1,2-diacyl-sn-glycerolipids to induce clockwise (+)-helicity around the 1,2-diacyl moiety: Evidence from conformation analysis by 1H NMR spectroscopy

Cell-membrane glycerolipids exhibit a common structural backbone of asymmetric 1,2-diacyl-sn-glycerol bearing polar head groups in the sn-3 position. In this study, the possible effects of sn-3 head groups on the helical conformational property around the 1,2-diacyl moiety in the solution state were...

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Bibliographic Details
Main Authors: Yoshihiro Nishida, Mengfei Yuan, Kazuo Fukuda, Kaito Fujisawa, Hirofumi Dohi, Hirotaka Uzawa
Format: Article
Language:English
Published: Beilstein-Institut 2017-09-01
Series:Beilstein Journal of Organic Chemistry
Subjects:
cell membrane
chirality
conformation
deuterium labeling
sn-glycerol
glycerolipids
glycerophospholipids
helicity
Karplus equation
proton NMR spectroscopy
staggered conformers
Online Access:https://doi.org/10.3762/bjoc.13.196

Internet

https://doi.org/10.3762/bjoc.13.196

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