Molecular-Clinical Correlation in Pediatric Medulloblastoma: A Cohort Series Study of 52 Cases in Taiwan

Molecular-Clinical Correlation in Pediatric Medulloblastoma: A Cohort Series Study of 52 Cases in Taiwan

In 2016, a project was initiated in Taiwan to adopt molecular diagnosis of childhood medulloblastoma (MB). In this study, we aimed to identify a molecular-clinical correlation and somatic mutation for exploring risk-adapted treatment, drug targets, and potential genetic predisposition. In total, 52...

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Main Authors: Kuo-Sheng Wu, Donald Ming-Tak Ho, Shiann-Tarng Jou, Alice L. Yu, Huy Minh Tran, Muh-Lii Liang, Hsin-Hung Chen, Yi-Yen Lee, Yi-Wei Chen, Shih-Chieh Lin, Feng-Chi Chang, Min-Lan Tsai, Yen-Lin Liu, Hsin-Lun Lee, Kevin Li-Chun Hsieh, Wen-Chang Huang, Shian-Ying Sung, Che-Chang Chang, Chun Austin Changou, Kung-Hao Liang, Tsung-Han Hsieh, Yun-Ru Liu, Meng-En Chao, Wan Chen, Shing-Shung Chu, Er-Chieh Cho, Tai-Tong Wong
Format: Article
Language:English
Published: MDPI AG 2020-03-01
Series:Cancers
Subjects:
medulloblastoma
molecular–clinical correlation
risk stratification
rna-seq
somatic mutations
dna damage response
genetic predisposition
Online Access:https://www.mdpi.com/2072-6694/12/3/653

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