Cardiac Targeting Peptide, a Novel Cardiac Vector: Studies in Bio-Distribution, Imaging Application, and Mechanism of Transduction

Cardiac Targeting Peptide, a Novel Cardiac Vector: Studies in Bio-Distribution, Imaging Application, and Mechanism of Transduction

Our previous work identified a 12-amino acid peptide that targets the heart, termed cardiac targeting peptide (CTP). We now quantitatively assess the bio-distribution of CTP, show a clinical application with the imaging of the murine heart, and study its mechanisms of transduction. Bio-distribution...

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Bibliographic Details
Main Authors: Maliha Zahid, Kyle S. Feldman, Gabriel Garcia-Borrero, Timothy N. Feinstein, Nicholas Pogodzinski, Xinxiu Xu, Raymond Yurko, Michael Czachowski, Yijen L. Wu, Neale S. Mason, Cecilia W. Lo
Format: Article
Language:English
Published: MDPI AG 2018-11-01
Series:Biomolecules
Subjects:
cardiac targeting peptide
cell penetrating peptides
protein transduction domains
mechanism of transduction
bio-distribution
SPECT imaging
Online Access:https://www.mdpi.com/2218-273X/8/4/147

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https://www.mdpi.com/2218-273X/8/4/147

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