Isoform‐resolved correlation analysis between mRNA abundance regulation and protein level degradation

Isoform‐resolved correlation analysis between mRNA abundance regulation and protein level degradation

Abstract Profiling of biological relationships between different molecular layers dissects regulatory mechanisms that ultimately determine cellular function. To thoroughly assess the role of protein post‐translational turnover, we devised a strategy combining pulse stable isotope‐labeled amino acids...

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Bibliographic Details
Main Authors: Barbora Salovska, Hongwen Zhu, Tejas Gandhi, Max Frank, Wenxue Li, George Rosenberger, Chongde Wu, Pierre‐Luc Germain, Hu Zhou, Zdenek Hodny, Lukas Reiter, Yansheng Liu
Format: Article
Language:English
Published: Wiley 2020-03-01
Series:Molecular Systems Biology
Subjects:
alternative splicing
DIA mass spectrometry
protein turnover
proteomics
pulsed SILAC
Online Access:https://doi.org/10.15252/msb.20199170

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