Evaluating cell lines as models for metastatic breast cancer through integrative analysis of genomic data
While cell lines and organoids are extensively used to study cancer, how closely they resemble the disease in patients remains unclear. Here, Liu et al. shed light on this issue by comparing the genomic and transcriptomic profiles of different breast cancer cell lines and organoids to data from pati...
Main Authors: | Ke Liu, Patrick A. Newbury, Benjamin S. Glicksberg, William Z. D. Zeng, Shreya Paithankar, Eran R. Andrechek, Bin Chen |
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Format: | Article |
Language: | English |
Published: |
Nature Publishing Group
2019-05-01
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Series: | Nature Communications |
Online Access: | https://doi.org/10.1038/s41467-019-10148-6 |
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