A rapid access to aliphatic sulfonyl fluorides

Sulfonyl fluorides are important probes in chemical biology and molecular pharmacology. Here, the authors report a mild visible light-mediated decarboxylative fluorosulfonylethylation for the synthesis of aliphatic sulfonyl fluorides from a wide range of carboxylic acids, including natural products...

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Bibliographic Details
Main Authors: Ruting Xu, Tianxiao Xu, Mingcheng Yang, Tianpeng Cao, Saihu Liao
Format: Article
Language:English
Published: Nature Publishing Group 2019-08-01
Series:Nature Communications
Online Access:https://doi.org/10.1038/s41467-019-11805-6