The Capricious Nature of Bacterial Pathogens: Phasevarions and Vaccine Development

The Capricious Nature of Bacterial Pathogens: Phasevarions and Vaccine Development

Infectious diseases are a leading cause of morbidity and mortality worldwide, and vaccines are one of the most successful and cost-effective tools for disease prevention. One of the key considerations for rational vaccine development is the selection of appropriate antigens. Antigens must induce a p...

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Bibliographic Details
Main Authors: Aimee Tan, John M Atack, Michael P Jennings, Kate L Seib
Format: Article
Language:English
Published: Frontiers Media S.A. 2016-12-01
Series:Frontiers in Immunology
Subjects:
Gene Expression
epigenetics
Vaccine
Phase Variation
DNA methyltransferase
DNA modification enzyme
Online Access:http://journal.frontiersin.org/Journal/10.3389/fimmu.2016.00586/full

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