Subchronic exposure to phytoestrogens alone and in combination with diethylstilbestrol - pituitary tumor induction in Fischer 344 rats
<p>Abstract</p> <p>Background</p> <p>Subchronic administration of the potent pharmaceutical estrogen diethylstilbestrol (DES) to female Fischer 344 (F344) rats induces growth of large, hemorrhagic pituitaries that progress to tumors. Phytoestrogens (dietary plant estrog...
Main Authors: | , , , , |
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Format: | Article |
Language: | English |
Published: |
BMC
2010-05-01
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Series: | Nutrition & Metabolism |
Online Access: | http://www.nutritionandmetabolism.com/content/7/1/40 |