A suspected case of hypoxia-induced pre-renal azotemia in an old part-Arab stallion: case report and review of the literature

The kidneys maintain homeostasis and this function is compromised in hypoxic conditions. Hematology and serum biochemistry evaluations were performed on a 17-year old Nigerian part-Arab stallion, who was observed to be docile, cachexic, and has bilateral ocular mucus discharge. Ticks were seen attac...

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Main Authors: Onyinyechukwu A. AGINA, Ezinne C. ANI
Format: Article
Language:English
Published: University of Agricultural Sciences and Veterinary Medicine, Cluj-Napoca 2020-06-01
Series:Notulae Scientia Biologicae
Subjects:
Online Access:https://www.notulaebiologicae.ro/index.php/nsb/article/view/10637
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spelling doaj-7e964f11ec2647e4a9bf39dd302039c62020-11-25T03:38:31ZengUniversity of Agricultural Sciences and Veterinary Medicine, Cluj-NapocaNotulae Scientia Biologicae2067-32052067-32642020-06-0112210.15835/nsb12210637A suspected case of hypoxia-induced pre-renal azotemia in an old part-Arab stallion: case report and review of the literatureOnyinyechukwu A. AGINA0Ezinne C. ANI1University of Nigeria, Faculty of Veterinary Medicine, Department of Veterinary Pathology and Microbiology, NsukkaUniversity of Nigeria, Faculty of Veterinary Medicine, Department of Veterinary Pathology and Microbiology, NsukkaThe kidneys maintain homeostasis and this function is compromised in hypoxic conditions. Hematology and serum biochemistry evaluations were performed on a 17-year old Nigerian part-Arab stallion, who was observed to be docile, cachexic, and has bilateral ocular mucus discharge. Ticks were seen attached around the inguinal region. The mucous membrane of the eyes was congested, animal was partially insensitive to its environment and had an abnormal posture and gait. Blood samples for hematology and clinical biochemistry analyses were collected from the jugular vein. Hematology and serum biochemistry determinations followed standard procedures. Hematological analysis revealed that the stallion had secondary absolute polycythemia, low erythrocyte sedimentation rate. The mean corpuscular volume, mean corpuscular hemoglobin concentration and total leukocyte count were within the respective reference ranges. The clinical biochemistry profile of the horse showed normal serum activity of alanine aminotransferase and elevated serum activities of aspartate aminotransferase and alkaline phosphatase, normal serum total protein, albumin, decreased serum globulin concentrations, with a high albumin: globulin (A/G) ratio. The stallion also had normal total cholesterol level and an abnormally high serum creatinine and blood urea nitrogen levels. These findings were suggestive of hypoxia-induced pre-renal azotemia. https://www.notulaebiologicae.ro/index.php/nsb/article/view/10637hematology; hypoxia; serum biochemistry; old stallion; part-Arab; pre-renal azotemia
collection DOAJ
language English
format Article
sources DOAJ
author Onyinyechukwu A. AGINA
Ezinne C. ANI
spellingShingle Onyinyechukwu A. AGINA
Ezinne C. ANI
A suspected case of hypoxia-induced pre-renal azotemia in an old part-Arab stallion: case report and review of the literature
Notulae Scientia Biologicae
hematology; hypoxia; serum biochemistry; old stallion; part-Arab; pre-renal azotemia
author_facet Onyinyechukwu A. AGINA
Ezinne C. ANI
author_sort Onyinyechukwu A. AGINA
title A suspected case of hypoxia-induced pre-renal azotemia in an old part-Arab stallion: case report and review of the literature
title_short A suspected case of hypoxia-induced pre-renal azotemia in an old part-Arab stallion: case report and review of the literature
title_full A suspected case of hypoxia-induced pre-renal azotemia in an old part-Arab stallion: case report and review of the literature
title_fullStr A suspected case of hypoxia-induced pre-renal azotemia in an old part-Arab stallion: case report and review of the literature
title_full_unstemmed A suspected case of hypoxia-induced pre-renal azotemia in an old part-Arab stallion: case report and review of the literature
title_sort suspected case of hypoxia-induced pre-renal azotemia in an old part-arab stallion: case report and review of the literature
publisher University of Agricultural Sciences and Veterinary Medicine, Cluj-Napoca
series Notulae Scientia Biologicae
issn 2067-3205
2067-3264
publishDate 2020-06-01
description The kidneys maintain homeostasis and this function is compromised in hypoxic conditions. Hematology and serum biochemistry evaluations were performed on a 17-year old Nigerian part-Arab stallion, who was observed to be docile, cachexic, and has bilateral ocular mucus discharge. Ticks were seen attached around the inguinal region. The mucous membrane of the eyes was congested, animal was partially insensitive to its environment and had an abnormal posture and gait. Blood samples for hematology and clinical biochemistry analyses were collected from the jugular vein. Hematology and serum biochemistry determinations followed standard procedures. Hematological analysis revealed that the stallion had secondary absolute polycythemia, low erythrocyte sedimentation rate. The mean corpuscular volume, mean corpuscular hemoglobin concentration and total leukocyte count were within the respective reference ranges. The clinical biochemistry profile of the horse showed normal serum activity of alanine aminotransferase and elevated serum activities of aspartate aminotransferase and alkaline phosphatase, normal serum total protein, albumin, decreased serum globulin concentrations, with a high albumin: globulin (A/G) ratio. The stallion also had normal total cholesterol level and an abnormally high serum creatinine and blood urea nitrogen levels. These findings were suggestive of hypoxia-induced pre-renal azotemia.
topic hematology; hypoxia; serum biochemistry; old stallion; part-Arab; pre-renal azotemia
url https://www.notulaebiologicae.ro/index.php/nsb/article/view/10637
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