Prognostic Values of Filamin-A Status for Topoisomerase II Poison Chemotherapy

Prognostic Values of Filamin-A Status for Topoisomerase II Poison Chemotherapy

<p>Filamin-A, also called Actin Binding Protein-280, is not only an essential component of the cytoskeleton networks, but also serves as the scaffold in various signaling networks. It has been shown that filamin-A facilitates DNA repair and filamin-A proficient cells are more resistant to ioni...

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Bibliographic Details
Main Author: Jingyin Yue, Shijie Lan, Changji Yuan, Zhiyuan Shen
Format: Article
Language:English
Published: Ivyspring International Publisher 2012-01-01
Series:International Journal of Biological Sciences
Online Access:http://www.biolsci.org/v08p0442.htm

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