Active p21-Activated Kinase 1 Rescues MCF10A Breast Epithelial Cells from Undergoing Anoikis

The protein kinase, PAKi, is overexpressed in human breast cancer and may contribute to malignancy through induction of proliferation and invasiveness. In this study, we examined the role of PAKi in the survival of detached MCF10A breast epithelial cells to test whether it may also regulate the ear...

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Bibliographic Details
Main Authors: Raymond E. Menard, Andrew P. Jovanovski, Raymond R. Mattingly
Format: Article
Language:English
Published: Elsevier 2005-07-01
Series:Neoplasia: An International Journal for Oncology Research
Subjects:
Online Access:http://www.sciencedirect.com/science/article/pii/S1476558605800855