Quercetin and histamine effects on free radical reactions in rat erythrocytes

The effects of quercetin and histamine separately or in combination on the free radical state of rat erythrocytes were estimated in vitro. Quercetin (0.1; 0.5; 3.0; 5.0 mM) or histamine (0.01; 10.0 μM) were added to whole blood separately or in combination. The content of hydroperoxides, TBA-active...

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Main Authors:	N. P. Harasym, M. Y. Booklyv, A. R. Zyn, S. M. Mandzynets, A. O. Bezkorovainy, D. I. Sanahursky
Format:	Article
Language:	English
Published:	National Academy of Sciences of Ukraine and Palladin Institute of Biochemistry of the National Academy of Sciences of Ukraine. 2021-02-01
Series:	Ukrainian Biochemical Journal
Subjects:	histamine quercetin erythrocytes lipid peroxidation proteins carbonyl groups
Online Access:	http://ukrbiochemjournal.org/wp-content/uploads/2021/02/Harasym_1_21.pdf

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spelling	doaj-7e65a28d6b8a4d2db97b4754d39ac66b2021-03-04T12:29:50ZengNational Academy of Sciences of Ukraine and Palladin Institute of Biochemistry of the National Academy of Sciences of Ukraine.Ukrainian Biochemical Journal2409-49432413-50032021-02-019319610310.15407/ubj93.01.096Quercetin and histamine effects on free radical reactions in rat erythrocytesN. P. Harasym0https://orcid.org/0000-0002-6102-4271M. Y. Booklyv1A. R. Zyn2S. M. Mandzynets3https://orcid.org/0000-0003-3053-628XA. O. Bezkorovainy4D. I. Sanahursky5https://orcid.org/0000-0002-8998-7117Ivan Franko National University of Lviv, Faculty of Biology, Departments of Biophysics and Bioinformatics, Lviv, UkraineIvan Franko National University of Lviv, Faculty of Biology, Departments of Biophysics and Bioinformatics, Lviv, UkraineIvan Franko National University of Lviv, Faculty of Biology, Departments of Biophysics and Bioinformatics, Lviv, UkraineIvan Franko National University of Lviv, Faculty of Biology, Departments of Biophysics and Bioinformatics, Lviv, UkraineIvan Franko National University of Lviv, Faculty of Biology, Departments of Biophysics and Bioinformatics, Lviv, UkraineIvan Franko National University of Lviv, Faculty of Biology, Departments of Biophysics and Bioinformatics, Lviv, UkraineThe effects of quercetin and histamine separately or in combination on the free radical state of rat erythrocytes were estimated in vitro. Quercetin (0.1; 0.5; 3.0; 5.0 mM) or histamine (0.01; 10.0 μM) were added to whole blood separately or in combination. The content of hydroperoxides, TBA-active products and carbonyl groups of proteins in erythrocytes after hemolysis was determined. The greatest influence of quercetin and histamine on erythrocytes state indicators was revealed under their combined action, when the level of TBA-active products and the content of carbonyl groups of proteins were found to be increased substantially.http://ukrbiochemjournal.org/wp-content/uploads/2021/02/Harasym_1_21.pdfhistaminequercetinerythrocyteslipid peroxidationproteins carbonyl groups
collection	DOAJ
language	English
format	Article
sources	DOAJ
author	N. P. Harasym M. Y. Booklyv A. R. Zyn S. M. Mandzynets A. O. Bezkorovainy D. I. Sanahursky
spellingShingle	N. P. Harasym M. Y. Booklyv A. R. Zyn S. M. Mandzynets A. O. Bezkorovainy D. I. Sanahursky Quercetin and histamine effects on free radical reactions in rat erythrocytes Ukrainian Biochemical Journal histamine quercetin erythrocytes lipid peroxidation proteins carbonyl groups
author_facet	N. P. Harasym M. Y. Booklyv A. R. Zyn S. M. Mandzynets A. O. Bezkorovainy D. I. Sanahursky
author_sort	N. P. Harasym
title	Quercetin and histamine effects on free radical reactions in rat erythrocytes
title_short	Quercetin and histamine effects on free radical reactions in rat erythrocytes
title_full	Quercetin and histamine effects on free radical reactions in rat erythrocytes
title_fullStr	Quercetin and histamine effects on free radical reactions in rat erythrocytes
title_full_unstemmed	Quercetin and histamine effects on free radical reactions in rat erythrocytes
title_sort	quercetin and histamine effects on free radical reactions in rat erythrocytes
publisher	National Academy of Sciences of Ukraine and Palladin Institute of Biochemistry of the National Academy of Sciences of Ukraine.
series	Ukrainian Biochemical Journal
issn	2409-4943 2413-5003
publishDate	2021-02-01
description	The effects of quercetin and histamine separately or in combination on the free radical state of rat erythrocytes were estimated in vitro. Quercetin (0.1; 0.5; 3.0; 5.0 mM) or histamine (0.01; 10.0 μM) were added to whole blood separately or in combination. The content of hydroperoxides, TBA-active products and carbonyl groups of proteins in erythrocytes after hemolysis was determined. The greatest influence of quercetin and histamine on erythrocytes state indicators was revealed under their combined action, when the level of TBA-active products and the content of carbonyl groups of proteins were found to be increased substantially.
topic	histamine quercetin erythrocytes lipid peroxidation proteins carbonyl groups
url	http://ukrbiochemjournal.org/wp-content/uploads/2021/02/Harasym_1_21.pdf
work_keys_str_mv	AT npharasym quercetinandhistamineeffectsonfreeradicalreactionsinraterythrocytes AT mybooklyv quercetinandhistamineeffectsonfreeradicalreactionsinraterythrocytes AT arzyn quercetinandhistamineeffectsonfreeradicalreactionsinraterythrocytes AT smmandzynets quercetinandhistamineeffectsonfreeradicalreactionsinraterythrocytes AT aobezkorovainy quercetinandhistamineeffectsonfreeradicalreactionsinraterythrocytes AT disanahursky quercetinandhistamineeffectsonfreeradicalreactionsinraterythrocytes
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Quercetin and histamine effects on free radical reactions in rat erythrocytes

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