Quercetin and histamine effects on free radical reactions in rat erythrocytes

The effects of quercetin and histamine separately or in combination on the free radical state of rat erythrocytes were estimated in vitro. Quercetin (0.1; 0.5; 3.0; 5.0 mM) or histamine (0.01; 10.0 μM) were added to whole blood separately or in combination. The content of hydroperoxides, TBA-active...

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Bibliographic Details
Main Authors: N. P. Harasym, M. Y. Booklyv, A. R. Zyn, S. M. Mandzynets, A. O. Bezkorovainy, D. I. Sanahursky
Format: Article
Language:English
Published: National Academy of Sciences of Ukraine and Palladin Institute of Biochemistry of the National Academy of Sciences of Ukraine. 2021-02-01
Series:Ukrainian Biochemical Journal
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Online Access:http://ukrbiochemjournal.org/wp-content/uploads/2021/02/Harasym_1_21.pdf
Description
Summary:The effects of quercetin and histamine separately or in combination on the free radical state of rat erythrocytes were estimated in vitro. Quercetin (0.1; 0.5; 3.0; 5.0 mM) or histamine (0.01; 10.0 μM) were added to whole blood separately or in combination. The content of hydroperoxides, TBA-active products and carbonyl groups of proteins in erythrocytes after hemolysis was determined. The greatest influence of quercetin and histamine on erythrocytes state indicators was revealed under their combined action, when the level of TBA-active products and the content of carbonyl groups of proteins were found to be increased substantially.
ISSN:2409-4943
2413-5003