The Restoration of Vitamin D Levels Slows the Progression of Renal Ischemic Injury in Rats Previously Deficient in Vitamin D

The Restoration of Vitamin D Levels Slows the Progression of Renal Ischemic Injury in Rats Previously Deficient in Vitamin D

Chronic kidney disease (CKD) remains a global public health problem. The initial damage after ischemia/reperfusion (I/R) injury plays an important role in the pathogenesis of acute kidney injury (AKI) and predisposition to CKD. Several studies have been showing that nontraditional risk factors such...

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Bibliographic Details
Main Authors: Michele Santiago dos Santos, Daniele Canale, Desiree Rita Denelle Bernardo, Maria Heloisa Massola Shimizu, Antonio Carlos Seguro, Rildo Aparecido Volpini, Ana Carolina de Bragança
Format: Article
Language:English
Published: Frontiers Media S.A. 2021-04-01
Series:Frontiers in Medicine
Subjects:
kidney disease progression
ischemia/reperfusion injury
vitamin D deficiency
vitamin D replacement
inflammation
fibrosis
Online Access:https://www.frontiersin.org/articles/10.3389/fmed.2021.625647/full

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