Lipopolysaccharide stimulates the secretion of the amyloid precursor protein via a protein kinase C-mediated pathway

Lipopolysaccharide stimulates the secretion of the amyloid precursor protein via a protein kinase C-mediated pathway

The processing of the amyloid precursor protein (APP) by the secretase family of protease enzymes can be influenced by a variety of diverse factors, including elements of the immune response. In this study, we have investigated the effect of the pro-inflammatory lipopolysaccharide (LPS) on APP proce...

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Bibliographic Details
Main Authors: Claire I. Small, Geoffrey A. Lyles, Kieran C. Breen
Format: Article
Language:English
Published: Elsevier 2005-08-01
Series:Neurobiology of Disease
Subjects:
Alzheimer
Amyloid
Lipopolysaccharide
Glia
Protein kinase C
Online Access:http://www.sciencedirect.com/science/article/pii/S0969996105000318

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