INFECTIVE ENDOCARDITIS IN ELDERLY: FROM ETIOLOGY TO TREATMENT AND PREVENTION

• Main Authors: N. T. Vatutin, G. G. Taradin, E. A. Tchaus, A. S. Smirnova
• Format: Article
• Language: Russian
• Published: «FIRMA «SILICEA» LLC 2016-01-01
• Series: Российский кардиологический журнал
• Subjects: infective endocarditis; elderly; etiology; antibiotics; treatment; prevention
• Online Access: https://russjcardiol.elpub.ru/jour/article/view/639
• ISSN: 1560-4071; 2618-7620

The review reflects the changes of epidemiological profile of infective endocarditis (IE) with an increase of prevalence in elderly. The risk factors are discussed, including anamnesis of various endocardium diseases, artificial valves implantation, different treatments or diagnostic procedures and especially cardiosurgical interventions. Among risk factors, predisposing to the infectious involvement of endocardium in elderly, are calcification of leaflets, age-related changes, diabetes, inflammatory diseases of gastrointestinal and urogenital tracts. The specifics of etiological spectrum of IE microbes is presented, with increased prevalence of S. bovis endocarditis, enterococcus, coagulase-negative staphylococci, in comparison with younger patients. The review focuses on microbiological diagnostics as one of the main criteria of IE. Approaches to treatment of the disease are shown with general principles, selection of empirical therapy and prescription of relevantantibacterial drugs after obtaining of bacteriological results of hemoculture. The principles of treatment of the elderly are based upon expert Guidelines of European Society of Cardiology and American Heart Association, published in 2015. The importance underlined of prevention in higher risk groups and procedures of high risk, as of following general hygienic and sanitation norms.