Pneumococcal Polysaccharide Vaccine Ameliorates Murine Lupus

Pneumococcal Polysaccharide Vaccine Ameliorates Murine Lupus

Current guidelines encourage administering pneumococcal vaccine Prevnar-13 to patients with lupus, but whether such vaccinations affect disease severity is unclear. To address this issue, we treated 3-month-old MRL-lpr mice, that spontaneously develop a lupus-like syndrome, with Prevnar-13 or vehicl...

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Bibliographic Details
Main Authors: Chiara Cantarelli, Chiara Guglielmo, Susan Hartzell, Fadi El Salem, Sofia Andrighetto, Victor P. Gazivoda, Enrico Fiaccadori, Gaetano La Manna, Gianluigi Zaza, Jeremy Leventhal, Ioannis Tassiulas, Paolo Cravedi
Format: Article
Language:English
Published: Frontiers Media S.A. 2019-11-01
Series:Frontiers in Immunology
Subjects:
lupus
prevnar
vaccination
TFH
TFR
Online Access:https://www.frontiersin.org/article/10.3389/fimmu.2019.02695/full

Internet

https://www.frontiersin.org/article/10.3389/fimmu.2019.02695/full

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