The Citrus Flavonoid Naringenin Protects the Myocardium from Ageing-Dependent Dysfunction: Potential Role of SIRT1

The Citrus Flavonoid Naringenin Protects the Myocardium from Ageing-Dependent Dysfunction: Potential Role of SIRT1

Sirtuin 1 (SIRT1) enzyme plays a pivotal role in the regulation of many physiological functions. In particular, it is implicated in ageing-related diseases, such as cardiac hypertrophy, myocardial infarct, and endothelial dysfunction; moreover, its expression decreases with age. Therefore, an effect...

Full description

Bibliographic Details
Main Authors:	Lara Testai, Eugenia Piragine, Ilaria Piano, Lorenzo Flori, Eleonora Da Pozzo, Vincenzo Miragliotta, Andrea Pirone, Valentina Citi, Lorenzo Di Cesare Mannelli, Simone Brogi, Sara Carpi, Alma Martelli, Paola Nieri, Claudia Martini, Carla Ghelardini, Claudia Gargini, Vincenzo Calderone
Format:	Article
Language:	English
Published:	Hindawi Limited 2020-01-01
Series:	Oxidative Medicine and Cellular Longevity
Online Access:	http://dx.doi.org/10.1155/2020/4650207

Similar Items

The Citrus Flavanone Naringenin Protects Myocardial Cells against Age-Associated Damage
by: Eleonora Da Pozzo, et al.
Published: (2017-01-01)

Role of hydrogen sulfide in endothelial dysfunction: Pathophysiology and therapeutic approaches
by: Valentina Citi, et al.
Published: (2021-01-01)

A Nutraceutical Strategy to Slowing Down the Progression of Cone Death in an Animal Model of Retinitis Pigmentosa
by: Ilaria Piano, et al.
Published: (2019-05-01)

Development of In Vitro Corneal Models: Opportunity for Pharmacological Testing
by: Valentina Citi, et al.
Published: (2020-11-01)

Modulation of EndMT by Hydrogen Sulfide in the Prevention of Cardiovascular Fibrosis
by: Lara Testai, et al.
Published: (2021-06-01)

The H<sub>2</sub>S-Donor Erucin Exhibits Protective Effects against Vascular Inflammation in Human Endothelial and Smooth Muscle Cells
by: Alma Martelli, et al.
Published: (2021-06-01)

Structure-activity relationships study of isothiocyanates for H2S releasing properties: 3-Pyridyl-isothiocyanate as a new promising cardioprotective agent
by: Valentina Citi, et al.
Published: (2021-01-01)

The Nutraceutical Value of Olive Oil and Its Bioactive Constituents on the Cardiovascular System. Focusing on Main Strategies to Slow Down Its Quality Decay during Production and Storage
by: Flori Lorenzo, et al.
Published: (2019-08-01)

<i>Eruca sativa</i> Meal against Diabetic Neuropathic Pain: An H<sub>2</sub>S-Mediated Effect of Glucoerucin
by: Elena Lucarini, et al.
Published: (2019-08-01)

Inhibitory effect of naringenin on LPS-induced skin senescence by SIRT1 regulation in HDFs
by: Kye Hwa Lim, et al.
Published: (2018-11-01)

Efficacy of isothiocyanate-based compounds on different forms of persistent pain
by: Lucarini E, et al.
Published: (2018-11-01)

Palmitoylethanolamide Counteracts Enteric Inflammation and Bowel Motor Dysfunctions in a Mouse Model of Alzheimer’s Disease
by: Vanessa D’Antongiovanni, et al.
Published: (2021-09-01)

A New Calcium Oral Controlled-Release System Based on Zeolite for Prevention of Osteoporosis
by: Angela Fabiano, et al.
Published: (2019-10-01)

Mitochondriotropic and Cardioprotective Effects of Triphenylphosphonium-Conjugated Derivatives of the Diterpenoid Isosteviol
by: Lara Testai, et al.
Published: (2017-09-01)

Naringin and Naringenin Pharmacokinetics and the Influence of Naringenin on Cyclosporin Absorption
by: TANG-YEN HUANG, et al.
Published: (1999)

Antioxidant and Antisenescence Effects of Bergamot Juice
by: Eleonora Da Pozzo, et al.
Published: (2018-01-01)

Pharmacokinetics of naringenin
by: Shiao-Wei Peng, et al.
Published: (1999)

Naringenin reduces early brain injury in subarachnoid hemorrhage (SAH) mice: The role of the AMPK/SIRT3 signaling pathway
by: Hanhai Zeng, et al.
Published: (2020-09-01)

Coenzyme Q<sub>10</sub>: Clinical Applications beyond Cardiovascular Diseases
by: Lara Testai, et al.
Published: (2021-05-01)

Pharmacokinetic Comparisons of Naringenin and Naringenin-Nicotinamide Cocrystal in Rats by LC-MS/MS
by: Dan Xu, et al.
Published: (2020-01-01)

Neurorestoration from medicinal plants: an opportunity to treat painful neuropathies
by: Lorenzo Di Cesare Mannelli, et al.
Published: (2017-01-01)

Naringenin Nano-Delivery Systems and Their Therapeutic Applications
by: Mohammed Bhia, et al.
Published: (2021-02-01)

Tumor Suppressor Role of hsa-miR-193a-3p and -5p in Cutaneous Melanoma
by: Beatrice Polini, et al.
Published: (2020-08-01)

Cytotoxic, genotoxic and apoptotic effects of naringenin-oxime relative to naringenin on normal and cancer cell lines
by: Abdurrahim Kocyigit, et al.
Published: (2016-10-01)

Indogenous protection of the iscaemic myocardium
by: Gray, Caroline Claudia
Published: (2002)

Improved performance of naringenin herbosomes over naringenin in streptozotocin-induced diabetic rats: In vitro and in vivo evaluation
by: Ruthvika Joshi, et al.
Published: (2021-01-01)

Retinal Neurodegeneration: Correlation between Nutraceutical Treatment and Animal Model
by: Ilaria Piano, et al.
Published: (2021-02-01)

Mouse rods signal through gap junctions with cones
by: Sabrina Asteriti, et al.
Published: (2014-01-01)

Blueberry juice protects osteocytes and bone precursor cells against oxidative stress partly through SIRT1
by: Vladana Domazetovic, et al.
Published: (2019-06-01)

Effects of naringenin on the pharmacokinetics of tofacitinib in rats
by: Bo Wang, et al.
Published: (2020-01-01)

Physical Mixture Interaction of Acetaminophenol with Naringenin
by: Normyzatul Akmal Abd Malek, et al.
Published: (2018-02-01)

Physical Mixture Interaction of Acetaminophenol with Naringenin
by: Abd Malek, NA, et al.
Published: (2018)

Solvatochromism of naringenin in aqueous alcoholic mixtures
by: Faraji Mohammad, et al.
Published: (2016-01-01)

Novel Polymeric Biomaterial Based on Naringenin
by: Malgorzata Latos-Brozio, et al.
Published: (2021-04-01)

Physical mixture interaction of acetaminophenol with Naringenin
by: Jalil, M.N, et al.
Published: (2018)

Development of Fortified Citrus Olive Oils: From Their Production to Their Nutraceutical Properties on the Cardiovascular System
by: Lorenzo Flori, et al.
Published: (2020-05-01)

Computer-Driven Development of an in Silico Tool for Finding Selective Histone Deacetylase 1 Inhibitors
by: Hajar Sirous, et al.
Published: (2020-04-01)

Vascular Effects of the Polyphenolic Nutraceutical Supplement Taurisolo<sup>®</sup>: Focus on the Protection of the Endothelial Function
by: Alma Martelli, et al.
Published: (2021-05-01)

Treatment with acetyl-L-carnitine exerts a neuroprotective effect in the sciatic nerve following loose ligation: a functional and microanatomical study
by: Daniele Tomassoni, et al.
Published: (2018-01-01)

Mesenchymal stem cells, implications for pain therapy
by: Elena Trallori, et al.
Published: (2019-01-01)