Does DNA Exert an Active Role in Generating Cell-Sized Spheres in an Aqueous Solution with a Crowding Binary Polymer?

Does DNA Exert an Active Role in Generating Cell-Sized Spheres in an Aqueous Solution with a Crowding Binary Polymer?

We report the spontaneous generation of a cell-like morphology in an environment crowded with the polymers dextran and polyethylene glycol (PEG) in the presence of DNA. DNA molecules were selectively located in the interior of dextran-rich micro-droplets, when the composition of an aqueous two-phase...

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Bibliographic Details
Main Authors: Kanta Tsumoto, Masafumi Arai, Naoki Nakatani, Shun N. Watanabe, Kenichi Yoshikawa
Format: Article
Language:English
Published: MDPI AG 2015-02-01
Series:Life
Subjects:
DNA
dextran
polyethylene glycol (PEG)
crowding
aqueous two-phase system (ATPS)
optical tweezers
microcompartment
artificial cell model
Online Access:http://www.mdpi.com/2075-1729/5/1/459

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