Formulation development and evaluation of metformin chewing gum with bitter taste masking

Formulation development and evaluation of metformin chewing gum with bitter taste masking

Background: Medicated gums are intended to be chewed and act either locally, absorbed via the buccal mucosa or swallowed with saliva. We prepared the metformin gum to overcome its side effects including vomiting, diarrhea, and abdomen discomfort. Furthermore, it could be useful for those who have sw...

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Bibliographic Details
Main Authors: Sayed Abolfazl Mostafavi, Jaleh Varshosaz, Saber Arabian
Format: Article
Language:English
Published: Wolters Kluwer Medknow Publications 2014-01-01
Series:Advanced Biomedical Research
Subjects:
Acesulfame-isomalt
freeze drying
hedonic test
medicated chewing gum
metformin
Online Access:http://www.advbiores.net/article.asp?issn=2277-9175;year=2014;volume=3;issue=1;spage=92;epage=92;aulast=Mostafavi

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