Platelet activation via dynamic conformational changes of von Willebrand factor under shear.

Platelet activation via dynamic conformational changes of von Willebrand factor under shear.

Shear-induced conformational changes of von Willebrand factor (VWF) play an important role in platelet activation. A novel approach describing VWF unfolding on the platelet surface under dynamic shear stress is proposed. Cumulative effect of dynamic shear on platelet activation via conformational ch...

Full description

Bibliographic Details
Main Authors: Denis M Pushin, Tatiana Y Salikhova, Ksenia E Zlobina, Georgy Th Guria
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2020-01-01
Series:PLoS ONE
Online Access:https://doi.org/10.1371/journal.pone.0234501

Similar Items

Similar Items