Peptide modification results in the formation of a dimer with a 60-fold enhanced antimicrobial activity.

Peptide modification results in the formation of a dimer with a 60-fold enhanced antimicrobial activity.

Cationic antimicrobial peptides (CAMPs) occur naturally in numerous organisms and are considered as a class of antibiotics with promising potential against multi-resistant bacteria. Herein, we report a strategy that can lead to the discovery of novel small CAMPs with greatly enhanced antimicrobial a...

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Bibliographic Details
Main Authors: Amal Thamri, Myriam Létourneau, Alex Djoboulian, David Chatenet, Eric Déziel, Annie Castonguay, Jonathan Perreault
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2017-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC5351969?pdf=render

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http://europepmc.org/articles/PMC5351969?pdf=render

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