A threading-based method for the prediction of DNA-binding proteins with application to the human genome.

Diverse mechanisms for DNA-protein recognition have been elucidated in numerous atomic complex structures from various protein families. These structural data provide an invaluable knowledge base not only for understanding DNA-protein interactions, but also for developing specialized methods that pr...

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Bibliographic Details
Main Authors: Mu Gao, Jeffrey Skolnick
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2009-11-01
Series:PLoS Computational Biology
Online Access:http://europepmc.org/articles/PMC2770119?pdf=render