Cycle Inhibiting Factors (Cifs): Cyclomodulins That Usurp the Ubiquitin-Dependent Degradation Pathway of Host Cells

Cycle inhibiting factors (Cifs) are type III secreted effectors produced by diverse pathogenic bacteria. Cifs are “cyclomodulins” that inhibit the eukaryotic host cell cycle and also hijack other key cellular processes such as those controlling the actin network and apoptosis. This review summarizes...

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Bibliographic Details
Main Authors: Eric Oswald, Frédéric Taieb, Jean-Philippe Nougayrède
Format: Article
Language:English
Published: MDPI AG 2011-03-01
Series:Toxins
Subjects:
Online Access:http://www.mdpi.com/2072-6651/3/4/356/